Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1025671 |
| landingPage: |
http://www.iedb.org/assay/1976396 |
| type: |
Literature
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| publicationVenue: |
J Gen Virol
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| dates: |
2013
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| study type: | b cell assays |
| subject species: | Lake Victoria marburgvirus - Angola2005 |
| fullName: |
Masahiro Kajihara
Eri Nakayama
Andrea Marzi
Manabu Igarashi
Heinz Feldmann
Ayato Takada
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| method: |
ELISA
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| name: |
Novel mutations in Marburg virus glycoprotein associated with viral evasion from antibody mediated immune pressure.
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| description: |
The epitope-specific mAb bound the antigen in ELISA. Mutant rVSVDG/MARVGP that escapes from the epitope-specific mAb selective pressure were cloned. All the obtained MARV GP mutants showed a remarkable reduction in binding ability to the mAbs while there was no significant difference in overall expression levels between the mutant and parental GPs.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
