Monoclonal antibody against the turn of the 42-residue amyloid beta-protein at positions 22 and 23.

Title:

Monoclonal antibody against the turn of the 42-residue amyloid beta-protein at positions 22 and 23.

identifier:	1988587
description:	epitope description:VFFAE antigen name:Amyloid beta A4 protein host organism:Mus musculus antibody name:4G8
aggregation:	instance of dataset
availability:	available
primaryPublications:	22778811

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Kazuma Murakami Yuko Horikoshi-Sakuraba Nakaba Murata Yoshihiro Noda Yuichi Masuda Noriaki Kinoshita Hiroyuki Hatsuta Shigeo Murayama Takuji Shirasawa Takahiko Shimizu Kazuhiro Irie

method:	immuno staining

name:	Monoclonal antibody against the turn of the 42-residue amyloid beta-protein at positions 22 and 23.
description:	Immunohistochemical studies of epitope-specific mAb using the frontal lobe and hippocampus regions of autopsied brains from 17 Alzheimer's Disease (AD) and 18 non-AD individuals was performed. The age range of the AD patients was 74 to 96 years and of the non-Ad individuals 67 to 83 years. The epitope-specific mAb reacted with typical amyloid plaques in the frontal lobe of AD patients.

name:	iedb
homePage:	http://www.iedb.org

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