Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1026626 |
| landingPage: |
http://www.iedb.org/assay/1989907 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
2013
|
| study type: | b cell assays |
| subject species: | Human herpesvirus 5 strain AD169 |
| fullName: |
Nadja Spindler
Pia Rü
cker
Sonja Pö
tzsch
Uschi Diestel
Heinrich Sticht
Luis Martin-Parras
Thomas H Winkler
Michael Mach
|
| method: |
immuno staining
|
| name: |
Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus.
|
| description: |
The epitope-specific mAb bound Cos7 cells transfected with an expression vector for the AD-4 peptide. This peptide contains the aa 112 to 132, and 344 to 438 of the gB of the HCMV strain AD169. Loss of signal was seen for the mAbs with the KK378/79 mutant, in which lysine residues 378 and 379 were changed to alanine.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |