Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2004478 |
| description: |
epitope description:S555, T559, E562, A563, H583, R584, L585, S586, T587, R589, H608, M612, F619, L621, V622, M623, T624, Q625, T626, K1260, F1264, S1265, S1268
antigen name:Multidrug resistance protein 1A
host organism:Lama glama
antibody name:Nb592
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
23901103 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1026709 |
| landingPage: |
http://www.iedb.org/assay/2004478 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2013
|
| study type: | b cell assays |
| subject species: | Mus musculus |
| fullName: |
Andrew B Ward
Paul Szewczyk
Vinciane Grimard
Chang-Wook Lee
Lorena Martinez
Rupak Doshi
Alexandra Caya
Mark Villaluz
Els Pardon
Cristina Cregger
Douglas J Swartz
Pierre Guy Falson
Ina L Urbatsch
Cedric Govaerts
Jan Steyaert
Geoffrey Chang
|
| method: |
chromatography
|
| name: |
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
|
| description: |
The epitope-specific nanobody Nb592 formed a complex with mouse P-glycoprotein (P-gp; multidrug resistance protein 1A), as demonstrated by size exclusion chromatography and subsequently analyzed on SDS gels.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
