Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. |
| identifier: | 2004467 |
| description: |
epitope description:K324, Y325, R402, G405, P406, E458, F459, R460, P461, D462, L463, E465, M466, D469
antigen name:Insulin-degrading enzyme
host organism:Mus musculus
antibody name:Fab(IDE)
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
23922390 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1026706 |
| landingPage: |
http://www.iedb.org/assay/2004467 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2013
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Lauren A McCord
Wenguang G Liang
Evan Dowdell
Vasilios Kalas
Robert J Hoey
Akiko Koide
Shohei Koide
Wei-Jen Tang
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme.
|
| description: |
The epitope residues were calculated from [PDB: 4IOF] as the antigen residues at 4Å
atomic distance from the antibody.
The association rate constant for epitope-specific Fab(IDE) binding to the insulin-degrading enzyme (IDE) was determined by surface plasmon resonance.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |