Nature-inspired design of motif-specific antibody scaffolds. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Nature-inspired design of motif-specific antibody scaffolds.

Dataset

identifier:	2004878
description:	epitope description:GEKKGNYVVTTH + PHOS(T11) host organism:Mus musculus antibody name:pSTAb
aggregation:	instance of dataset
availability:	available
primaryPublications:	23955275

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1026708
landingPage:	http://www.iedb.org/assay/2004878

Publication

type:	Literature
publicationVenue:	Nat Biotechnol
dates:	2013

Dimension

study type:	b cell assays
subject species:

Person

fullName:	James T Koerber Nathan D Thomsen Brett T Hannigan William F Degrado James A Wells

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Nature-inspired design of motif-specific antibody scaffolds.
description:	The affinity of the pSer/pThr-specific Fab pSTAb for binding to the pThr containing epitope was determined by surface plasmon resonance. Fab pSTAb did not bind to the epitope with an unphosphorylated Thr or Ser residue at position 11.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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