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identifier: 2004517
description:
epitope description:A487
antigen name:Structural polyprotein
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 24069479
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026831
landingPage: http://www.iedb.org/assay/2004517
type:
Literature
publicationVenue:
PLoS Negl Trop Dis
dates:
2013
study type: b cell assays
subject species: Chikungunya virus
fullName:
Suganya Selvarajah
Nicole R Sexton
Kristen M Kahle
Rachel H Fong
Kimberly-Anne Mattia
Joy Gardner
Kai Lu
Nathan M Liss
Beatriz Salvador
David F Tucker
Trevor Barnes
Manu Mabila
Xiangdong Zhou
Giada Rossini
Joseph B Rucker
David Avram Sanders
Andreas Suhrbier
Vittorio Sambri
Alain Michault
Marcus O Muench
Benjamin J Doranz
Graham Simmons
method:
in vivo assay
name:
A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease.
description:
The epitope -specific mAb was able to protect B6 mice from viremia and arthritis.

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