Nature-inspired design of motif-specific antibody scaffolds. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Nature-inspired design of motif-specific antibody scaffolds.

Dataset

identifier:	2004905
description:	epitope description:KGNYVVTDH host organism:Mus musculus antibody name:Parent Fab
aggregation:	instance of dataset
availability:	available
primaryPublications:	23955275

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1026708
landingPage:	http://www.iedb.org/assay/2004905

Publication

type:	Literature
publicationVenue:	Nat Biotechnol
dates:	2013

Dimension

study type:	b cell assays
subject species:

Person

fullName:	James T Koerber Nathan D Thomsen Brett T Hannigan William F Degrado James A Wells

Data Type

method:	surface plasmon resonance (SPR)

Study

name:	Nature-inspired design of motif-specific antibody scaffolds.
description:	The affinity of the Asp-specific and epitope-reactive parent Fab for binding to the longer peptide was determined by surface plasmon resonance. The Fab did not bind to the peptide with a phosphorylated or unphosphorylated Thr or Ser residue at position 11.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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