Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.

Title:

Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.

Dataset

identifier:	2015856
description:	epitope description:KALRAWFNAGRSELAVSV + CITR(R4, R11) antigen name:Probable peptidylarginine deiminase host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	23463691

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1027038
landingPage:	http://www.iedb.org/assay/2015856

Publication

type:	Literature
publicationVenue:	Ann Rheum Dis
dates:	2014

Dimension

study type:	b cell assays
subject species:	Porphyromonas gingivalis

Person

fullName:	Anne-Marie Quirke Elena Birgitta Lugli Natalia Wegner Bart C Hamilton Peter Charles Muslima Chowdhury A Jimmy Ytterberg Roman A Zubarev Jan Potempa Shauna Culshaw Yonghua Guo Benjamin A Fisher Geoffrey Thiele Ted R Mikuls Patrick Jw Venables

Data Type

method:	ELISA

Study

name:	Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.
description:	The epitope contained an additional C- and N-terminal Cys residue.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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