Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2015846 |
| description: |
epitope description:A: S152, N153, W169, G174, S175, S202, T203, Q205, E206, T208, S209, G241, L242; C: T142, T144, P178, V179, N181
antigen name:Hemagglutinin
host organism:Mus musculus BALB/c
antibody name:HC63
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
11886266 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1032 |
| landingPage: |
http://www.iedb.org/assay/2015846 |
| type: |
Literature
|
| publicationVenue: |
Virology
|
| dates: |
2002
|
| study type: | b cell assays |
| subject species: | Influenza A virus |
| fullName: |
C Barbey-Martin
B Gigant
T Bizebard
L J Calder
S A Wharton
J J Skehel
M Knossow
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| method: |
ELISA
|
| name: |
An antibody that prevents the hemagglutinin low pH fusogenic transition.
|
| description: |
The epitope is located on HA1 chains of two monomers, with 5 residues (T142, T144, P178, V179, N181) bound in one monomer and 13 residues (S152, N153, W169, G174, S175, S202, T203, Q205, E206, S209, T208, G241, L242) bound in another. The epitope overlaps the sialic acid receptor-binding site.
The affinity of epitope-specific HC63 Fab for the HA on Influenza A virus A/X-31(H3N2)) was determined.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
