Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology.

Title:

Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology.

identifier:	2006256
description:	epitope description:SYSVQDQYQALLQQHAQYLK antigen name:Putative OmpA family lipoprotein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	23993463

study type:	b cell assays
subject species:	Burkholderia pseudomallei K96243

fullName:	Louise J Gourlay Claudio Peri Mario Ferrer-Navarro Oscar Conchillo-Solé Alessandro Gori Darawan Rinchai Rachael J Thomas Olivia L Champion Stephen L Michell Chidchamai Kewcharoenwong Arnone Nithichanon Patricia Lassaux Lucia Perletti Renato Longhi Ganjana Lertmemongkolchai Richard W Titball Xavier Daura Giorgio Colombo Martino Bolognesi

method:	ELISA

name:	Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology.
description:	Plasma samples from recovered melioidosis patients showed significantly more reactivity to the epitope than samples from healthy seronegative subjects from the endemic region. Residues 89-91 (YLK) were predicted to be part of an epitope.

name:	iedb
homePage:	http://www.iedb.org

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