Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology.

Title:

Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology.

identifier:	2006267
description:	epitope description:RSVYFDFDSYSVQDQYQALLQQHAQYLK antigen name:Putative OmpA family lipoprotein host organism:Oryctolagus cuniculus New Zealand White antibody name:anti-Pal(Bp)
aggregation:	instance of dataset
availability:	available
primaryPublications:	23993463

study type:	b cell assays
subject species:	Burkholderia pseudomallei K96243

fullName:	Louise J Gourlay Claudio Peri Mario Ferrer-Navarro Oscar Conchillo-Solé Alessandro Gori Darawan Rinchai Rachael J Thomas Olivia L Champion Stephen L Michell Chidchamai Kewcharoenwong Arnone Nithichanon Patricia Lassaux Lucia Perletti Renato Longhi Ganjana Lertmemongkolchai Richard W Titball Xavier Daura Giorgio Colombo Martino Bolognesi

method:	mass spectrometry

name:	Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology.
description:	The epitope was identified by partial trypsin or endoproteinase LysC digestion of Pal(Bp) and immunocapturing peptides with rabbit anti-Pal(Bp) antibodies. The bound epitope was identified by tandem mass spectrometry. The peptide 65-91 was also immunocaptured from the trypsin digest.

name:	iedb
homePage:	http://www.iedb.org

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