| identifier: | 2007000 |
| description: |
epitope description:beta-D-QuipN4Fm-(1->4)-alpha-D-GalpNAcAN-(1->4)-alpha-D-GalpNAcAN-(1->3)-beta-DQuipNAc-(1->2)-beta-D-QuipN4Fm-(1->4)-alpha-D-GalpNAcAN-(1->4)-alpha-D-GalpNAcAN-(1->3)-beta-DQuipNAc
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:Ab52
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
23844703 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1026604 |
| landingPage: |
http://www.iedb.org/assay/2007000 |
| type: |
Literature
|
| publicationVenue: |
Immunology
|
| dates: |
2013
|
| study type: | b cell assays |
| subject species: | Francisella tularensis |
| fullName: |
Zhaohua Lu
Michael J Rynkiewicz
Chiou-Ying Yang
Guillermo Madico
Hillary M Perkins
Qi Wang
Catherine E Costello
Joseph Zaia
Barbara A Seaton
Jacqueline Sharon
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.
|
| description: |
The epitope structure is composed two repeats of the O-Ag region of F. tularensis LPS. It can be found in Gunn and Ernst (2007) Ann N Y Acad Sci 1105: 202-218 [PMID:17395723].
The bivalent avidity of epitope-specific mAb for binding to chip-bound F. tularensis LPS was determined by surface plasmon resonance.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |