| identifier: | 2006756 |
| description: |
epitope description:E17, N18, A19, M20, P21, W22, N23, E118, D144, A145, Q146, S148, H149
antigen name:Dihydrofolate reductase (UniProt:P0ABQ4)
host organism:Lama glama
antibody name:Nb216
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
21238460 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1026760 |
| landingPage: |
http://www.iedb.org/assay/2006756 |
| type: |
Literature
|
| publicationVenue: |
J Mol Biol
|
| dates: |
2011
|
| study type: | b cell assays |
| subject species: | Escherichia coli K-12 |
| fullName: |
David Oyen
Vasundara Srinivasan
Jan Steyaert
John N Barlow
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition.
|
| description: |
The affinity of epitope-specific nanobody Nb216 for binding to apo-DHFR was determined by surface plasmon resonance.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |