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identifier: 2006756
description:
epitope description:E17, N18, A19, M20, P21, W22, N23, E118, D144, A145, Q146, S148, H149
antigen name:Dihydrofolate reductase (UniProt:P0ABQ4)
host organism:Lama glama
antibody name:Nb216
aggregation:
instance of dataset
availability:
available
primaryPublications: 21238460
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026760
landingPage: http://www.iedb.org/assay/2006756
type:
Literature
publicationVenue:
J Mol Biol
dates:
2011
study type: b cell assays
subject species: Escherichia coli K-12
fullName:
David Oyen
Vasundara Srinivasan
Jan Steyaert
John N Barlow
method:
surface plasmon resonance (SPR)
name:
Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition.
description:
The affinity of epitope-specific nanobody Nb216 for binding to apo-DHFR was determined by surface plasmon resonance.

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