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identifier: 2006991
description:
epitope description:beta-D-QuipN4Fm-(1->4)-alpha-D-GalpNAcAN-(1->4)-alpha-D-GalpNAcAN-(1->3)-beta-DQuipNAc
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:FB11
aggregation:
instance of dataset
availability:
available
primaryPublications: 23844703
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026604
landingPage: http://www.iedb.org/assay/2006991
type:
Literature
publicationVenue:
Immunology
dates:
2013
study type: b cell assays
subject species: Francisella tularensis
fullName:
Zhaohua Lu
Michael J Rynkiewicz
Chiou-Ying Yang
Guillermo Madico
Hillary M Perkins
Qi Wang
Catherine E Costello
Joseph Zaia
Barbara A Seaton
Jacqueline Sharon
method:
biological activity
name:
The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.
description:
The epitope structure is composed of one repeat of the O-Ag region of F. tularensis LPS. It can be found in Gunn and Ernst (2007) Ann N Y Acad Sci 1105: 202-218 [PMID:17395723].
The epitope-specific mAb agglutinated F. tularensis LVS (live vaccine strain).

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