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Title: Thermodynamic signatures of the antigen binding site of mAb 447-52D targeting the third variable region of HIV-1 gp120.
identifier: 2007039
description:
epitope description:CRIHIGPGRAFYTC + OX(C1, C14)
host organism:Homo sapiens
antibody name:447-52D
aggregation:
instance of dataset
availability:
available
primaryPublications: 23944979
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026762
landingPage: http://www.iedb.org/assay/2007039
type:
Literature
publicationVenue:
Biochemistry
dates:
2013
study type: b cell assays
subject species:
fullName:
April Killikelly
Hui-Tang Zhang
Brett Spurrier
Constance Williams
Miroslaw K Gorny
Susan Zolla-Pazner
Xiang-Peng Kong
method:
calorimetry
name:
Thermodynamic signatures of the antigen binding site of mAb 447-52D targeting the third variable region of HIV-1 gp120.
description:
The affinity of Fv 447-52D for the cyclic V3 epitope was determined by isothermal calorimetry. The ka = 0.063 1/M.

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