Ligand recognition by anti-DNA autoantibodies. Affinity, specificity, and mode of binding. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Ligand recognition by anti-DNA autoantibodies. Affinity, specificity, and mode of binding.

Dataset

identifier:	2007361
description:	epitope description:dT5 host organism:Mus musculus MLR/lpr antibody name:15D8, 9F11, 15B10, 8D8, 11F8
aggregation:	instance of dataset
availability:	available
primaryPublications:	8634294

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006970
landingPage:	http://www.iedb.org/assay/2007361

Publication

type:	Literature
publicationVenue:	Biochemistry
dates:	1996

Dimension

study type:	b cell assays
subject species:

Person

fullName:	P C Swanson C Ackroyd G D Glick

Data Type

method:	biological activity

Study

name:	Ligand recognition by anti-DNA autoantibodies. Affinity, specificity, and mode of binding.
description:	The epitope -specific mAbs bound the antigen, a 21-base-long oligomer containing a central dT5 segment flanked by a nonbinding region (dA8), as tested by Potassium permanganate foot printing. MAbs 15D8, 9F11, 15B10 are IgG2b, 8D8 is IgG2a, and 11F8 is IgG3.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.