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Title: Phl p 1-specific human monoclonal IgE and design of a hypoallergenic group 1 grass pollen allergen fragment.
identifier: 2007092
description:
epitope description:K176, N179, D223
antigen name:Phl p 1
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 23761636
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026425
landingPage: http://www.iedb.org/assay/2007092
type:
Literature
publicationVenue:
J Immunol
dates:
2013
study type: b cell assays
subject species: Phleum pratense
fullName:
Mattias Levin
Frida Rydnert
Eva Kä
llströ
m
Lor Wai Tan
Peter J Wormald
Malin Lindstedt
Lennart Greiff
Mats Ohlin
method:
biological activity
name:
Phl p 1-specific human monoclonal IgE and design of a hypoallergenic group 1 grass pollen allergen fragment.
description:
Basophils from patients recognized PhI p1. Mutations of K176, N179, and D224 led to loss of recognition. Changes in CD63 expression upon basophil degranulation were assessed.

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