Insight into structural diversity of influenza virus haemagglutinin. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Insight into structural diversity of influenza virus haemagglutinin.

Dataset

identifier:	2007099
description:	epitope description:E129, R130, F131, E132, P135, T137, S138, K180, S181, I183, Y270 antigen name:Hemagglutinin host organism:Mus musculus BALB/c antibody name:GC0757
aggregation:	instance of dataset
availability:	available
primaryPublications:	23636824

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1026826
landingPage:	http://www.iedb.org/assay/2007099

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	2013

Dimension

study type:	b cell assays
subject species:	Influenza A virus (A/Korea/01/2009(H1N1))

Person

fullName:	Ki Joon Cho Ji-Hye Lee Kwang W Hong Se-Ho Kim Yiho Park Jun Young Lee Seokha Kang Sella Kim Ji Hoon Yang Eui-Ki Kim Jong Hyeon Seok Satoru Unzai Sam Yong Park Xavier Saelens Chul-Joong Kim Joo-Yeon Lee Chun Kang Hee-Bok Oh Mi Sook Chung Kyung Hyun Kim

Data Type

method:	biological activity

Study

name:	Insight into structural diversity of influenza virus haemagglutinin.
description:	The epitope residues were calculated from [PDB: 4F15] as the antigen residues at 4Å atomic distance from the antibody. The epitope-specific mAb GC0757 neutralized the influenza A virus A/Brevig Mission/1/1918 (H1N1). The antibody neutralized H1N1 viruses, but did not neutralize influenza A virus A/Japan/305/1957 (H2N2) or A/bar-headed goose/Qinghai/14/2008 (H5N1).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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