Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2007721 |
| description: |
epitope description:D116, P119, D150, R151, A152, T153, N155, R156, R157, T158, D161, G162, I164, Q166, K208
antigen name:Granzyme K
host organism:Mus musculus A/J
antibody name:AFD
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
22362762 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1024620 |
| landingPage: |
http://www.iedb.org/assay/2007721 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2012
|
| study type: | b cell assays |
| subject species: | Macaca fascicularis |
| fullName: |
Kenneth J Katschke Jr
Ping Wu
Rajkumar Ganesan
Robert F Kelley
Mary A Mathieu
Philip E Hass
Jeremy Murray
Daniel Kirchhofer
Christian Wiesmann
Menno van Lookeren Campagne
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Inhibiting alternative pathway complement activation by targeting the factor D exosite.
|
| description: |
The epitope residues were calculated from [PDB: 4D9Q] as the antigen residues at 4Å
atomic distance from the antibody.
The affinity of epitope-specific AFD Fab for binding to cynomolgus Factor D was determined by surface plasmon resonance.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
