Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site. |
| identifier: | 2007979 |
| description: |
epitope description:K147, V149, T150, A151, G157, A158, K159, W167, A203, D204, Q206, S207, L208, K236, D239, Q240
antigen name:Hemagglutinin
host organism:Homo sapiens
antibody name:5J8
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
24027321 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1026803 |
| landingPage: |
http://www.iedb.org/assay/2007979 |
| type: |
Literature
|
| publicationVenue: |
J Virol
|
| dates: |
2013
|
| study type: | b cell assays |
| subject species: | Influenza A virus (A/California/07/2009(H1N1)) |
| fullName: |
Minsun Hong
Peter S Lee
Ryan M B Hoffman
Xueyong Zhu
Jens C Krause
Nick S Laursen
Sung-Il Yoon
Langzhou Song
Lynda Tussey
James E Crowe Jr
Andrew B Ward
Ian A Wilson
|
| method: |
bio-layer interferometry assay
|
| name: |
Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site.
|
| description: |
The epitope residues are calculated from [PDB: 4M5Z] as the antigen residues at 4Å
atomic distance from the antibody.
The affinity of epitope-specific antibody 5J8 IgG for binding to A/California/04/2009 H1 HA was determined by bio-layer interferometry using an Octet RED instrument. The 55J8 Fab bound more weakly, with KD of 5-50 nM.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |