High-avidity and potently neutralizing cross-reactive human monoclonal antibodies derived from secondary dengue virus infection.

Title:

High-avidity and potently neutralizing cross-reactive human monoclonal antibodies derived from secondary dengue virus infection.

identifier:	2012625
description:	epitope description:T76, W101, G106, L107, F108 antigen name:Genome polyprotein host organism:Homo sapiens antibody name:753C6, 753C8
aggregation:	instance of dataset
availability:	available
primaryPublications:	24027331

study type:	b cell assays
subject species:	Dengue virus

fullName:	Wen-Yang Tsai Chih-Yun Lai Yi-Chieh Wu Hong-En Lin Carolyn Edwards Amonrat Jumnainsong Srisakul Kliks Scott Halstead Juthathip Mongkolsapaya Gavin R Screaton Wei-Kung Wang

method:	ELISA

name:	High-avidity and potently neutralizing cross-reactive human monoclonal antibodies derived from secondary dengue virus infection.
description:	The epitope-specific mAbs recognized the antigen in ELISA. The epitope was determined by ELISA and a dot blot assay using lysates derived from 293T cells transfected with a wild-type (WT) DENV1 prM/E construct or of the 67 predicted surface-exposed E alanine mutants.

name:	iedb
homePage:	http://www.iedb.org

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