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identifier: 2012846
description:
epitope description:W101, F108
antigen name:Genome polyprotein
host organism:Homo sapiens
antibody name:DVG6.3, DVG7.5, 749B6
aggregation:
instance of dataset
availability:
available
primaryPublications: 24027331
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026944
landingPage: http://www.iedb.org/assay/2012846
type:
Literature
publicationVenue:
J Virol
dates:
2013
study type: b cell assays
subject species: Dengue virus
fullName:
Wen-Yang Tsai
Chih-Yun Lai
Yi-Chieh Wu
Hong-En Lin
Carolyn Edwards
Amonrat Jumnainsong
Srisakul Kliks
Scott Halstead
Juthathip Mongkolsapaya
Gavin R Screaton
Wei-Kung Wang
method:
biological activity
name:
High-avidity and potently neutralizing cross-reactive human monoclonal antibodies derived from secondary dengue virus infection.
description:
The epitope-specific mAbs neutralized the virus. The neutralization potency of each MAb was determined by the concentration that gave 50% inhibition in a focus reduction neutralization test (FRNT50 value).

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