A mouse monoclonal antibody against dengue virus type 1 Mochizuki strain targeting envelope protein domain II and displaying strongly neutralizing but not enhancing activity.

Title:

A mouse monoclonal antibody against dengue virus type 1 Mochizuki strain targeting envelope protein domain II and displaying strongly neutralizing but not enhancing activity.

Dataset

identifier:	2013027
description:	epitope description:K398 antigen name:Genome polyprotein host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	24049185

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1026943
landingPage:	http://www.iedb.org/assay/2013027

Publication

type:	Literature
publicationVenue:	J Virol
dates:	2013

Dimension

study type:	b cell assays
subject species:	Dengue virus 1 Mochizuki

Person

fullName:	Atsushi Yamanaka Tomohiro Kotaki Eiji Konishi

Data Type

method:	cross blocking

Study

name:	A mouse monoclonal antibody against dengue virus type 1 Mochizuki strain targeting envelope protein domain II and displaying strongly neutralizing but not enhancing activity.
description:	The epitope sequence was deduced by virus escape mutants. The epitopes-epcific mAb 7F4 was able to inhibit binding of the human DENV-1 reactive antiserum to the culture fluids of Vero cells infected with DENV-1.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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