In situ detection of acetylaminofluorene-DNA adducts in human cells using monoclonal antibodies. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

In situ detection of acetylaminofluorene-DNA adducts in human cells using monoclonal antibodies.

Dataset

identifier:	2014845
description:	epitope description:N-(deoxyguanosin-8-yl)-2-acetylaminofluorene host organism:Mus musculus BALB/c antibody name:AAF-1, AAF-2, AAF-3, AAF-4, AAF-5
aggregation:	instance of dataset
availability:	available
primaryPublications:	15380103

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016361
landingPage:	http://www.iedb.org/assay/2014845

Publication

type:	Literature
publicationVenue:	DNA Repair (Amst)
dates:	2004

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Taka-aki Iwamoto Nobuhiko Kobayashi Kyoko Imoto Aya Yamamoto Yu Nakamura Yukika Yamauchi Hiromi Okumura Akiko Tanaka Fumio Hanaoka Shinya Shibutani Sachiko Miyagawa Toshio Mori

Data Type

method:	antigen inhibition

Study

name:	In situ detection of acetylaminofluorene-DNA adducts in human cells using monoclonal antibodies.
description:	The epitope- specific mAbs bound to 2-acetylaminofluorene (AAF)-ssDNA and the epitope, complexed to 5'-CTCATCAACATCTTGAATTCACAATCAATA-3' with the epitope bound at G15, was able to compete for this binding. Smaller nucleosides were able to only weakly inhibit this binding. AFF-5 is IgG2a

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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