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Title: Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody.
identifier: 2019154
description:
epitope description:VSRQE
antigen name:Genome polyprotein
host organism:Mus musculus BALB/c
antibody name:4D10
aggregation:
instance of dataset
availability:
available
primaryPublications: 23987307
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026987
landingPage: http://www.iedb.org/assay/2019154
type:
Literature
publicationVenue:
BMC Microbiol
dates:
2013
study type: b cell assays
subject species: Dengue virus 2
fullName:
Ya-Yan Luo
Jun-Jie Feng
Jun-Mei Zhou
Zhi-Zhun Yu
Dan-Yun Fang
Hui-Jun Yan
Gu-Cheng Zeng
Li-Fang Jiang
method:
biological activity
name:
Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody.
description:
Enhancement of infection by the epitope-specific mAb was observed in antibody-dependent infection enhancement assay (ADE). Viral RNA levels were assessed and cytometry was performed in infected K562 cells.

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