Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain.

Title:

Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain.

identifier:	2019222
description:	epitope description:VQIINKKLDLSNVQSKC + DEAM(N5) antigen name:Microtubule-associated protein tau host organism:Oryctolagus cuniculus New Zealand White antibody name:anti-4R
aggregation:	instance of dataset
availability:	available
primaryPublications:	24252707

study type:	b cell assays
subject species:	Homo sapiens

fullName:	Ayaho Dan Muneaki Takahashi Masami Masuda-Suzukake Fuyuki Kametani Takashi Nonaka Hiromi Kondo Haruhiko Akiyama Takao Arai David M A Mann Yuko Saito Hiroyuki Hatsuta Shigeo Murayama Masato Hasegawa

method:	immuno staining

name:	Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain.
description:	The rabbit antibody stained formalin-fixed and formic acid or autoclave-treated brain sections of a patient with Alzheimer's disease. It also stained insoluble tau from three Alzheimer’s disease, two progressive supranuclear palsy and two corticobasal degeneration cases in a Western blot.

name:	iedb
homePage:	http://www.iedb.org

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