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Title: Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites.
identifier: 2019281
description:
epitope description:(S)-amphetamine
host organism:Mus musculus BALB/c
antibody name:scFv6H4
aggregation:
instance of dataset
availability:
available
primaryPublications: 24349338
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1027047
landingPage: http://www.iedb.org/assay/2019281
type:
Literature
publicationVenue:
PLoS One
dates:
2013
study type: b cell assays
subject species:
fullName:
Eric C Peterson
Reha Celikel
Kuppan Gokulan
Kottayil I Varughese
method:
x-ray crystallography
name:
Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites.
description:
The structure was solved by molecular replacement. The binding affinity of scFv6H4 to AMP was determined as KD = 20.7 µM (data not shown).

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