Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms.

Title:

Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms.

Dataset

identifier:	2019309
description:	epitope description:PDSRESLAWQTAT antigen name:Genome polyprotein host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	24131712

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1027066
landingPage:	http://www.iedb.org/assay/2019309

Publication

type:	Literature
publicationVenue:	J Virol
dates:	2014

Dimension

study type:	b cell assays
subject species:	Enterovirus A71

Person

fullName:	Xiaohua Ye Zhiqiang Ku Qingwei Liu Xiaoli Wang Jinping Shi Yunfang Zhang Liangliang Kong Yao Cong Zhong Huang

Data Type

method:	biological activity

Study

name:	Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms.
description:	The epitope sequence was deduced. The epitope-specific antiserum did not neutralize infection of RD cells by the virus.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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