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identifier: 2021166
description:
epitope description:4-nitrophenol
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 18350547
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1026246
landingPage: http://www.iedb.org/assay/2021166
type:
Literature
publicationVenue:
Eur J Immunol
dates:
2008
study type: b cell assays
subject species:
fullName:
T Scott Devera
Hemangi B Shah
Gillian A Lang
Mark L Lang
method:
ELISPOT
name:
Glycolipid-activated NKT cells support the induction of persistent plasma cell responses and antibody titers.
description:
The response in mice immunized with NP-KLH was enhanced by adjuvant alum or co-injection of alpha-GalCer. The alpha-GalCer variants, OCH or C-glycoside, were also effective in enhancing the response. The frequency of antibody-secreting cells was lower in CD1d-/- mice.

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