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Title: Alanine scanning mutagenesis of hepatitis C virus E2 cysteine residues: Insights into E2 biogenesis and antigenicity.
identifier: 2021394
description:
epitope description:C111, C125, C169, C181, C224, C261
antigen name:Genome polyprotein
host organism:Mus musculus
antibody name:H53
aggregation:
instance of dataset
availability:
available
primaryPublications: 24314653
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1027055
landingPage: http://www.iedb.org/assay/2021394
type:
Literature
publicationVenue:
Virology
dates:
2014
study type: b cell assays
subject species: Hepatitis C virus
fullName:
Wenbo Wang
Mo Guan
Yuan Liu
Qingqiang Xu
Haoran Peng
Xiaoqing Liu
Ziwei Tang
Yongzhe Zhu
Dage Wu
Hao Ren
Ping Zhao
Zhongtian Qi
method:
ELISA
name:
Alanine scanning mutagenesis of hepatitis C virus E2 cysteine residues: Insights into E2 biogenesis and antigenicity.
description:
The cysteine residues critical for antibody binding were determined by single alanine substitutions.

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