Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2021859 |
| description: |
epitope description:L2255, I2256, S2257, N2262, Y2263, I2278, E2279, K2281, F2283, F2285, M2291, Q2308, D2312, E2313, N2314, F2315, E2316
antigen name:Toxin B
host organism:Lama glama
antibody name:B39
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| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
24311789 |
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1027115 |
| landingPage: |
http://www.iedb.org/assay/2021859 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2014
|
| study type: | b cell assays |
| subject species: | Clostridioides difficile |
| fullName: |
Tomohiko Murase
Luiz Eugenio
Melissa Schorr
Greg Hussack
Jamshid Tanha
Elena N Kitova
John S Klassen
Kenneth K S Ng
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| method: |
mass spectrometry
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| name: |
Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile.
|
| description: |
The stoichiometry of epitope-specific B39 VHH binding to the TcdB-B1 RBD fragment (residues 2456-2710) was evaluated by electrospray ionization mass spectroscopy. The results show complexes with 1:1 and 2:1 (VHH: TcdB) stoichiometry, when B39 was present at 4-fold and 8-fold molar excess, respectively.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
