Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Structural characterization of the main immunogenic region of the Torpedo acetylcholine receptor. |
| identifier: | 2022314 |
| description: |
epitope description:E22, H23, E24, T25, R26, L27, V28, A29, K30, L31, F32, K33, D34, W80, V81, D82, Y83, N84, L85, K86, W87, N88, P89, D90, D91, Y92, G93, G94, V95, K96, K97, I98, H99, I100, P101
antigen name:Acetylcholine receptor subunit alpha (UniProt:P02708)
host organism:Rattus norvegicus Sprague-Dawley
antibody name:mAb 35
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
24333757 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1027151 |
| landingPage: |
http://www.iedb.org/assay/2022314 |
| type: |
Literature
|
| publicationVenue: |
Mol Immunol
|
| dates: |
2014
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Stuart W Morell
Vu B Trinh
Eswari Gudipati
Alexander Friend
Nelson A Page
Mark A Agius
David P Richman
Robert H Fairclough
|
| method: |
ELISA
|
| name: |
Structural characterization of the main immunogenic region of the Torpedo acetylcholine receptor.
|
| description: |
The epitope was defined in Luo et al J Neurosci 2009
29:13898 [PMID 19890000].
The epitope-specific mAb 35 bound T. californica AChR in a competitive ELISA. This mAb inhibited the binding of another AChR/MIR-specific mAb 132A.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |