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Title: Active and passive immunization strategies based on the SDPM1 peptide demonstrate pre-clinical efficacy in the APPswePSEN1dE9 mouse model for Alzheimer's disease.
identifier: 2023139
description:
epitope description:AECDWGKGGRWRLWPGASGKTEACGP
host organism:Mus musculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 24021662
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1027085
landingPage: http://www.iedb.org/assay/2023139
type:
Literature
publicationVenue:
Neurobiol Dis
dates:
2014
study type: b cell assays
subject species:
fullName:
Marybeth Camboni
Chiou-Miin Wang
Carlos Miranda
Jung Hae Yoon
Rui Xu
Deborah Zygmunt
Brian K Kaspar
Paul T Martin
method:
in vivo assay
name:
Active and passive immunization strategies based on the SDPM1 peptide demonstrate pre-clinical efficacy in the APPswePSEN1dE9 mouse model for Alzheimer's disease.
description:
Amyloid plaque burden and plaque number were significantly reduced in areas injected with the epitope-specific mAb.

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