Active and passive immunization strategies based on the SDPM1 peptide demonstrate pre-clinical efficacy in the APPswePSEN1dE9 mouse model for Alzheimer's disease.

Title:

Active and passive immunization strategies based on the SDPM1 peptide demonstrate pre-clinical efficacy in the APPswePSEN1dE9 mouse model for Alzheimer's disease.

Dataset

identifier:	2023309
description:	epitope description:AECDWGKGGRWRLWPGASGKTEACGP host organism:Mus musculus antibody name:P4D6
aggregation:	instance of dataset
availability:	available
primaryPublications:	24021662

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1027085
landingPage:	http://www.iedb.org/assay/2023309

Publication

type:	Literature
publicationVenue:	Neurobiol Dis
dates:	2014

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Marybeth Camboni Chiou-Miin Wang Carlos Miranda Jung Hae Yoon Rui Xu Deborah Zygmunt Brian K Kaspar Paul T Martin

Data Type

method:	biological activity

Study

name:	Active and passive immunization strategies based on the SDPM1 peptide demonstrate pre-clinical efficacy in the APPswePSEN1dE9 mouse model for Alzheimer's disease.
description:	The epitope-specific mAb inhibits Abeta amyloid-mediated neurotoxicity of retinoic acid differentiated SH-SY5Y cells.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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