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identifier: 2110099
description:
epitope description:H141, D199, A200, A201, E202, N209, P210, P227, N260
antigen name:Hemagglutinin
host organism:Mus musculus BALB/c
antibody name:HAb21
aggregation:
instance of dataset
availability:
available
primaryPublications: 24681124
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1027637
landingPage: http://www.iedb.org/assay/2110099
type:
Literature
publicationVenue:
Antiviral Res
dates:
2014
study type: b cell assays
subject species: Influenza A virus (A/Viet Nam/1203/2004(H5N1))
fullName:
Ruiping Wu
Xingxing Li
Ho-Chuen Leung
Zhiliang Cao
Zonglin Qiu
Yusen Zhou
Bo-Jian Zheng
Yuxian He
method:
biological activity
name:
A novel neutralizing antibody against diverse clades of H5N1 influenza virus and its mutants capable of airborne transmission.
description:
The epitope-specific mAb was able to neutralize infection of MDCK cells by the pseudovirus. The epitope-specific mAb could maintain it's high activity to inhibit pseudoviruses with multiple substitutions, such as N154D/N220K/Q222L, N154D/N220K/T315I, N154D/Q222L/T315I, and N154D/N220K/Q222L/T315I.

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