Identification of a novel overlapping sequential E epitope (E') on the bovine leukaemia virus SU glycoprotein and analysis of immunological data.

Title:

Identification of a novel overlapping sequential E epitope (E') on the bovine leukaemia virus SU glycoprotein and analysis of immunological data.

identifier:	2110254
description:	epitope description:SDWVPSVRSWA antigen name:gp60 SU host organism:Mus musculus BALB/c antibody name:2G7
aggregation:	instance of dataset
availability:	available
primaryPublications:	24916842

study type:	b cell assays
subject species:	Bovine leukemia virus

fullName:	Katia Forti Giorgia Rizzo Monica Cagiola Giovanna Ferrante Carla Marini Francesco Feliziani Giovanni Pezzotti Antonio De Giuseppe

method:	ELISA

name:	Identification of a novel overlapping sequential E epitope (E') on the bovine leukaemia virus SU glycoprotein and analysis of immunological data.
description:	The epitope was deduced. The epitope-specific mAb 2G7 was shown to bind the native recombinant protein. Fine mapping using deleted forms of the protein showed that the epitope was at the C-terminus of the surface envelope glycoprotein subunit (SU), residues 189-199. This was also shown by western blot.

name:	iedb
homePage:	http://www.iedb.org

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