B-cell epitopes in GroEL of Francisella tularensis. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

B-cell epitopes in GroEL of Francisella tularensis.

Dataset

identifier:	2113801
description:	epitope description:FEDEL antigen name:60 kDa chaperonin host organism:Mus musculus BALB/c antibody name:N30
aggregation:	instance of dataset
availability:	available
primaryPublications:	24968190

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1027962
landingPage:	http://www.iedb.org/assay/2113801

Publication

type:	Literature
publicationVenue:	PLoS One
dates:	2014

Dimension

study type:	b cell assays
subject species:	Francisella tularensis subsp. holarctica LVS

Person

fullName:	Zhaohua Lu Michael J Rynkiewicz Guillermo Madico Sheng Li Chiou-Ying Yang Hillary M Perkins Seshi R Sompuram Vani Kodela Tong Liu Timothy Morris Daphne Wang Marly I Roche Barbara A Seaton Jacqueline Sharon

Data Type

method:	hydrogen/deuterium exchange

Study

name:	B-cell epitopes in GroEL of Francisella tularensis.
description:	The epitope was deduced. The epitope of mAb N30 on rGroEL from strain LVS was mapped by hydrogen/deuterium exchange-mass spectroscopy (DXMS). The region of residues 183-187 showed reduced deuterium exchange in the presence of the antibody.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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