Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2110661 |
| description: |
epitope description:Y126, H129, Q133, A136, E137, T140, H141, Q147, N148, R149, Y150, T151, F152, A153, F154, R160, L164, Y189, L196
antigen name:rRNA N-glycosidase (UniProt:B9T8T0)
host organism:Vicugna pacos
antibody name:VHH1 (E5)
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
24907552 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1027972 |
| landingPage: |
http://www.iedb.org/assay/2110661 |
| type: |
Literature
|
| publicationVenue: |
J Mol Biol
|
| dates: |
2014
|
| study type: | b cell assays |
| subject species: | Ricinus communis |
| fullName: |
Michael J Rudolph
David J Vance
Jonah Cheung
Matthew C Franklin
Fiana Burshteyn
Michael S Cassidy
Ebony N Gary
Cristina Herrera
Charles B Shoemaker
Nicholas J Mantis
|
| method: |
biological activity
|
| name: |
Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.
|
| description: |
The epitope residues were calculated from [PDB: 4LGP] as the antigen residues at 4Å
atomic distance from the antibody.
The epitope-specific VHH1 (E5) neutralized ricin toxin in a Vero cell cytotoxicity assay.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
