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identifier: 2110669
description:
epitope description:Y126, H129, Q133, A136, E137, T140, H141, Q147, N148, R149, Y150, T151, F152, A153, F154, R160, L164, Y189, L196
antigen name:rRNA N-glycosidase (UniProt:B9T8T0)
host organism:Vicugna pacos
antibody name:VHH1 (E5)
aggregation:
instance of dataset
availability:
available
primaryPublications: 24907552
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1027972
landingPage: http://www.iedb.org/assay/2110669
type:
Literature
publicationVenue:
J Mol Biol
dates:
2014
study type: b cell assays
subject species: Ricinus communis
fullName:
Michael J Rudolph
David J Vance
Jonah Cheung
Matthew C Franklin
Fiana Burshteyn
Michael S Cassidy
Ebony N Gary
Cristina Herrera
Charles B Shoemaker
Nicholas J Mantis
method:
surface plasmon resonance (SPR)
name:
Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.
description:
The epitope residues were calculated from [PDB: 4LGP] as the antigen residues at 4Å
atomic distance from the antibody.
The affinity of epitope-specific VHH1 (E5) for binding to ricin (RTA) was determined by surface plasmon resonance.

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