Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2110988 |
| description: |
epitope description:E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
antigen name:Toxin B
host organism:Mus musculus HuMAb (Medarex)
antibody name:Bezlotoxumab
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
24821719 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1027969 |
| landingPage: |
http://www.iedb.org/assay/2110988 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2014
|
| study type: | b cell assays |
| subject species: | Clostridium difficile VPI 10463 |
| fullName: |
Peter Orth
Li Xiao
Lorraine D Hernandez
Paul Reichert
Payal R Sheth
Maribel Beaumont
Xiaoyu Yang
Nicholas Murgolo
Grigori Ermakov
Edward DiNunzio
Fred Racine
Jerzy Karczewski
Susan Secore
Richard N Ingram
Todd Mayhood
Corey Strickland
Alex G Therien
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.
|
| description: |
The epitope-specific mAb bound to the toxin as measured at the low affinity binding site by SPR.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
