Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1027969 |
| landingPage: |
http://www.iedb.org/assay/2110997 |
| type: |
Literature
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| publicationVenue: |
J Biol Chem
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| dates: |
2014
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| study type: | b cell assays |
| subject species: | Clostridium difficile VPI 10463 |
| fullName: |
Peter Orth
Li Xiao
Lorraine D Hernandez
Paul Reichert
Payal R Sheth
Maribel Beaumont
Xiaoyu Yang
Nicholas Murgolo
Grigori Ermakov
Edward DiNunzio
Fred Racine
Jerzy Karczewski
Susan Secore
Richard N Ingram
Todd Mayhood
Corey Strickland
Alex G Therien
|
| method: |
biological activity
|
| name: |
Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.
|
| description: |
The epitope-specific mAb was shown to neutralize the cytotoxic effects of the toxin on Vero cells by blocking binding of the toxin to the cell surface.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
