Epitope mapping of the HSP83.1 protein of Leishmania braziliensis discloses novel targets for immunodiagnosis of tegumentary and visceral clinical forms of leishmaniasis.

Title:

Epitope mapping of the HSP83.1 protein of Leishmania braziliensis discloses novel targets for immunodiagnosis of tegumentary and visceral clinical forms of leishmaniasis.

Dataset

identifier:	2111199
description:	epitope description:EVAEAPPAEAAPA antigen name:Heat shock protein 83-1 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	24807053

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1027967
landingPage:	http://www.iedb.org/assay/2111199

Publication

type:	Literature
publicationVenue:	Clin Vaccine Immunol
dates:	2014

Dimension

study type:	b cell assays
subject species:	Leishmania braziliensis MHOM/BR/75/M2904

Person

fullName:	Daniel Menezes-Souza Tiago Antô nio de Oliveira Mendes Matheus de Souza Gomes Joã o Luí s Reis-Cunha Ronaldo Alves Pinto Nagem Clá udia Martins Carneiro Eduardo Antô nio Ferraz Coelho Lú cia Maria da Cunha Galvã o Ricardo Toshio Fujiwara Daniella Castanheira Bartholomeu

Data Type

method:	ELISA

Study

name:	Epitope mapping of the HSP83.1 protein of Leishmania braziliensis discloses novel targets for immunodiagnosis of tegumentary and visceral clinical forms of leishmaniasis.
description:	Predicted linear B-cell epitopes were tested against human sera for reactivity. In a seaparate assay, the IgG reactivity against rHSP83.1 after the depletion of antibodies against the epitope was reduced.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.