Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2112949 |
| description: |
epitope description:A: H45, S46, S306, T333; B: V362, D363, G364, W365, L382, K385, T386, Q387, N388, I389, D390, T393, N397, I400, E401
antigen name:Hemagglutinin
host organism:Homo sapiens
antibody name:FI6v3-scFv
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
24927560 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1027960 |
| landingPage: |
http://www.iedb.org/assay/2112949 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
2014
|
| study type: | b cell assays |
| subject species: | H1N1 subtype |
| fullName: |
Vamsee V A Mallajosyula
Michael Citron
Francesca Ferrara
Xianghan Lu
Cheryl Callahan
Gwendolyn J Heidecker
Siddhartha P Sarma
Jessica A Flynn
Nigel J Temperton
Xiaoping Liang
Raghavan Varadarajan
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection.
|
| description: |
The epitope was provided in cited reference Corti et al. Science 2011
333:850-856 [PMID:21798894].
The affinity of the broadly neutralizing antibody (bnAb) was tested against a stem only construct of HA consisting of residues 18-41 (HA1) GSA linker 290-323 (HA1) GSAGSA linker 41-113 (HA2) QGTGG
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
