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identifier: 2114728
description:
epitope description:A: H24, H44, Q46, S304, M305, B: V364, D365, G366, W367, K384, T387, Q388, I391, T395, V398, N399, I402
antigen name:Hemagglutinin
host organism:Homo sapiens
antibody name:F10-scFv
aggregation:
instance of dataset
availability:
available
primaryPublications: 24927560
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1027960
landingPage: http://www.iedb.org/assay/2114728
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2014
study type: b cell assays
subject species: H5N1 subtype
fullName:
Vamsee V A Mallajosyula
Michael Citron
Francesca Ferrara
Xianghan Lu
Cheryl Callahan
Gwendolyn J Heidecker
Siddhartha P Sarma
Jessica A Flynn
Nigel J Temperton
Xiaoping Liang
Raghavan Varadarajan
method:
surface plasmon resonance (SPR)
name:
Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection.
description:
The epitope was provided in cited reference Sui et al. Nat Struct Mol Bio 2009
16:265-273 [PMID:19234466].
The affinity of the broadly neutralizing antibody (bnAb) was tested against recombinant HA.

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