Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 2117398 |
| description: |
epitope description:A: L314, Y315, T317; B: N36, D38, T40, T42, W48, N50, R51, W52, N53, S72, N73, T74, G78, G80, F81, A82
antigen name:Shiga toxin 1 B subunit
host organism:Lama glama
antibody name:NbStx2e1
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
25053417 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1028061 |
| landingPage: |
http://www.iedb.org/assay/2117398 |
| type: |
Literature
|
| publicationVenue: |
J Biol Chem
|
| dates: |
2014
|
| study type: | b cell assays |
| subject species: | Escherichia coli |
| fullName: |
Alvin W H Lo
Kristof Moonens
Maia De Kerpel
Lea Brys
Els Pardon
Han Remaut
Henri De Greve
|
| method: |
surface plasmon resonance (SPR)
|
| name: |
The molecular mechanism of Shiga toxin Stx2e neutralization by a single-domain antibody targeting the cell receptor-binding domain.
|
| description: |
The epitope residues were calculated from [PDB: 4P2C] as the antigen residues at 4Å
atomic distance from the antibody.
The affinity of epitope-specific nanobody NbStx2e1 for binding to Stx2e toxoid was determined by surface plasmon resonance.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
