Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis.

Dataset

identifier:	2118473
description:	epitope description:LYQEARKIVGAMVQIITYR antigen name:Myeloperoxidase host organism:Mus musculus HLA-DRB1*1501 Tg
aggregation:	instance of dataset
availability:	available
primaryPublications:	23549081

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1025761
landingPage:	http://www.iedb.org/assay/2118473

Publication

type:	Literature
publicationVenue:	J Clin Invest
dates:	2013

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Aleeza J Roth Joshua D Ooi Jacob J Hess Mirjan M van Timmeren Elisabeth A Berg Caroline E Poulton JulieAnne McGregor Madelyn Burkart Susan L Hogan Yichun Hu Witold Winnik Patrick H Nachman Coen A Stegeman John Niles Peter Heeringa A Richard Kitching Stephen Holdsworth J Charles Jennette Gloria A Preston Ronald J Falk

Data Type

method:	mass spectrometry

Study

name:	Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis.
description:	This conserved sequence is also present in mouse. Sera from mice immunized with the epitope reacted with other MPO peptides.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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