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identifier: 3113461
description:
epitope description:VKNPYPISF
antigen name:Human polyomavirus 2 protein
host organism:Homo sapiens
mhc allele name:HLA-A*02:01
aggregation:
instance of dataset
availability:
available
primaryPublications: 27705933
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1031221
landingPage: http://www.iedb.org/assay/3113461
type:
Literature
publicationVenue:
Oncotarget
dates:
2017
study type: t cell assays
subject species: JC polyomavirus
fullName:
Jiju Mani
Lei Wang
Angela G Hü
ckelhoven
Anita Schmitt
Alma Gedvilaite
Nan Jin
Christian Kleist
Anthony D Ho
Michael Schmitt
method:
in vitro assay
name:
Definition and characterization of novel HLA-*A02-restricted CD8+ T cell epitopes derived from JCV polyomavirus with clinical relevance.
description:
Epitope mapping using adjacent 9-mers comprising the length of the 15-mer (285-299) found to be positive in >30% of subjects revealed the shorter 288-296 peptide as optimal. Cytotoxicity was measured by the calcein-acetoxymethyl assay.

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