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Title: Definition and characterization of novel HLA-*A02-restricted CD8+ T cell epitopes derived from JCV polyomavirus with clinical relevance.
identifier: 3113469
description:
epitope description:SMLNLHAGS
antigen name:Human polyomavirus 1 protein
host organism:Homo sapiens
mhc allele name:HLA class I
aggregation:
instance of dataset
availability:
available
primaryPublications: 27705933
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1031221
landingPage: http://www.iedb.org/assay/3113469
type:
Literature
publicationVenue:
Oncotarget
dates:
2017
study type: t cell assays
subject species: BK virus strain AS
fullName:
Jiju Mani
Lei Wang
Angela G Hü
ckelhoven
Anita Schmitt
Alma Gedvilaite
Nan Jin
Christian Kleist
Anthony D Ho
Michael Schmitt
method:
ELISPOT
name:
Definition and characterization of novel HLA-*A02-restricted CD8+ T cell epitopes derived from JCV polyomavirus with clinical relevance.
description:
CD8+ T cells from healthy donors were primed in vitro with VLPs and were then tested for reactivity against the epitope. This JC polyomavirus-homologous peptide from BK polyomavirus was found to be negative. This peptide differs at critical anchor residues 2 and 9.

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