Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases.

Dataset

identifier:	3133693
description:	epitope description:IWYINCFGCETHAML antigen name:Glucose-6-phosphate isomerase (UniProt:P06744) host organism:Mus musculus C57BL/6
aggregation:	instance of dataset
availability:	available
primaryPublications:	27861821

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1031364
landingPage:	http://www.iedb.org/assay/3133693

Publication

type:	Literature
publicationVenue:	Immunology
dates:	2017

Dimension

study type:	t cell assays
subject species:	Homo sapiens

Person

fullName:	Anthony C Y Yau Fredrik Piehl Tomas Olsson Rikard Holmdahl

Data Type

method:	in vivo assay

Study

name:	Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases.
description:	The epitope sequence is found in Pizzolla A et al., Am J Pathol. 2013 Oct;183(4):1144-55 [PMID:23911657]. Mice immunized with the epitope developed arthritis, similar results were seen in both wild type and C2ta congenic mice. Younger mice (9-14 weeks) had a lower incidence of disease (74%).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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